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Archive for January, 2008



Hydromorphone: A Review

Published on January 24, 2008

Hydromorphone is a semi-synthetic opioid discovered in Germany in 1921 and introduced into clinical practice in 1926. Hydromorphone is structurally similar to morphine acting on ? receptors and, to a lesser extent, delta receptors. This drug is often considered a second-line drug for pain management.
Hydromorphone is four to five times more potent than morphine sulfate, [...]


Consumate Quality is Our Top Priority

Published on

At Hartley Medical, we strive to maintain the optimal environment for compounding sterile drugs. Long before the United States Pharmacopeia (USP) Chapter 797’s guidelines for sterile compounding were introduced, Hartley Medical had an effective environmental monitoring program that incorporates advanced technology.
For the last decade, we have monitored microbial air quality with the use of passive plates [...]


Baclofen: A Review

Published on

Baclofen is an agonist of gamma-amminobutyric acid (GABA), an inhibitory neurotransmitter, which acts on receptors in the brainstem and dorsal horn of the spinal cord. The drug is used primarily in the treatment of such conditions as spinal cord injury, cerebral palsy, and multiple sclerosis; however, the chemical also possesses analgesic properties. Intraspinal administration of [...]